1335Transfer and Persistence of Antibodies in Infants Following Maternal Immunization with an Investigational Trivalent Group B Streptococcus Vaccine

نویسندگان

  • Scott A Halperin
  • Gilbert Donders
  • Roland Devlieger
  • Sherryl Baker
  • Pietro Forte
  • Frederick Wittke
  • Karen Slobod
  • Peter M Dull
چکیده

1335. Transfer and Persistence of Antibodies in Infants Following Maternal Immunization with an Investigational Trivalent Group B Streptococcus Vaccine Scott A Halperin,; Gilbert Donders,; Roland Devlieger,; Sherryl Baker,; Pietro Forte,; Frederick Wittke,; Karen Slobod, MD; Peter M Dull, MD; Dalhousie University, Canadian Center for Vaccinology, Halifax, NS, Canada; Femicare Clinical Research for Women, Tienen, Belgium; Dept Obstetrics and Gynaecology, Regional Hospital H Hart, Tienen, Belgium; University Hospital Antwerpen, Antwerp, Belgium; Dept Obstetrics and Gynaecology, University Hospital Gasthuisberg, Leuven, Belgium; Novartis Vaccines and Diagnostics,Inc., Cambridge, MA

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Antibody Kinetics and Response to Routine Vaccinations in Infants Born to Women Who Received an Investigational Trivalent Group B Streptococcus Polysaccharide CRM197-Conjugate Vaccine During Pregnancy

Background Maternal vaccination against group B Streptococcus (GBS) might provide protection against invasive GBS disease in infants. We investigated the kinetics of transplacentally transferred GBS serotype-specific capsular antibodies in the infants and their immune response to diphtheria toxoid and pneumococcal vaccination. Methods This phase 1b/2, observer-blind, single-center study (NCT0...

متن کامل

Study of Immune Response in Infants of Non-Gestational Diabetic Mothers

Background Infants of diabetic mothers (IDMs) have significantly greater risk for spontaneous abortion, stillbirth, congenital malformations and perinatal mortality and morbidity but whether maternal DM affects the neonatal innate immune system is unknown. We aimed to assess the immune response of infants of diabetic mothers (IDMs) with non-gestational DM for Hepatitis B vaccine and to compare ...

متن کامل

Persistence of immunity to hepatitis B vaccine as infants, 17 years earlier

Background: In Iran scince 1992, hepatitis B vaccination was a part of the national vaccination program. Hepatitis B vaccination is effective in the epidemiology of hepatitis B. The aim ofthis study was to evaluate the long – term persistence of immunity. Methods: This cross-sectional analytical study was conducted on children and adolescents aged between 6-18 years in Birjand, who recei...

متن کامل

Early immunization of neonates with trivalent oral poliovirus vaccine.

Described is the evaluation in Brazil of the immune response of early immunization with trivalent oral poliovirus vaccine (TOPV). A total of 85 normal neonates from São Paulo were assigned one of the following immunization schedules: group A--one dose of TOPV at birth and subsequent doses at 2, 4, and 9 months of age; or group B--one dose of TOPV at 2, 4 and 6 months of age. Blood samples were ...

متن کامل

Maternal antibodies to pneumolysin but not to pneumococcal surface protein A delay early pneumococcal carriage in high-risk Papua New Guinean infants.

Immunization of pregnant women can be an efficient strategy to induce early protection in infants in developing countries. Pneumococcal protein-based vaccines may have the capacity to induce pneumococcal serotype-independent protection. To understand the potential of maternal pneumococcal protein-specific antibodies in infants in high-risk areas, we studied the placental transfer of naturally a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 1  شماره 

صفحات  -

تاریخ انتشار 2014